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DXA Services

Dual energy X-ray absorptiometry (DXA) is an efficient, noninvasive, low-radiation dose measurement of bone mineral content (BMC), bone mineral density (BMD), and total body composition (fat and fat-free mass). It’s currently the most common imaging tool used to determine BMD for disease processes such as osteoporosis. DXA offers low-radiation dosing (1/10 of the typical chest X-ray), rapid scan time, and ease of use. These distinctive attributes make DXA widely popular in the clinical research arena especially in trials employing bone density as a safety or efficacy endpoint.

DXA Services at CoreLab Partners
Our comprehensive DXA quality assurance program includes centralized DXA analysis in a rigorous, quality controlled environment with secure Internet transfer of image data. In addition, we oversee instrument quality control with extensive training and qualification of site DXA operators. CoreLab Partners’ processes are backed by innovative technologies and dedicated project teams with broad scientific, clinical, regulatory, and technical expertise.

CoreLab Partners’ robust DXA manager (DXM) platform accepts and processes all patient scans, and readies them for QC, review, and analysis using leading DXA manufacturers’ software. The DXM extracts the analysis and consolidates the results from all manufacturers into one secure, scalable Oracle database. Best of all, it’s integrated with RadSTART^SM - CoreLab Partners’ proprietary technology solution specifically designed to track, manage, and report on digital medical image data. RadSTART provides custom and standard real-time DXA reports that can be accessed at any time, from any location, via our secure sponsor portal - Coreview. Integration of these advanced technologies, coupled with proactive monitoring of data transfers, translate into invaluable time and money saving efficiencies.

Key Features

• Protocol specific & standard procedural training
• Instrument quality control
• Interface with Hologic or GE Lunar
• DXM integrated with RadSTART
• Image data acquisition via Internet
• Scanner cross calibration and longitudinal performance monitoring across sites
• 21 CFR and GCP compliant with full audit trail
• Experienced central DXA analysis

Key Benefits

• Secure access to tracking and reporting information, 24/7
• Near zero data loss through manual handling
• Built-in efficiencies from proven processes
• Clean, valid data guarantee that any observed density changes are real and not due to machine or operator variability
• Time and money resource savings
• Optimized regulatory submission process
• Rapid turnaround, 24/7 customer support
• Board-certified radiologists on staff for consult
• Multicentered standardization of DXA equipment